Harley Street Medical District, London

Has Your Anti-Wrinkle Treatment Stopped Lasting the Way It Used To?

If your results feel weaker, shorter-lived, or simply ‘not what they were,’ you’re not imagining it — and you’re not out of options. Book a private consultation to understand why, and what can be done.

Regulated by the Care Quality Commission · 20,000+ treatments performed · 4.9 on Google

A familiar conversation

You’re Not the Only One

It’s a conversation we have often at Sol Clinic: patients who have had Botulinum Toxin Type A (the standard anti-wrinkle treatment) for years, sometimes with excellent results early on, who now find the effect fading faster — or not appearing at all. This isn’t about the wrong practitioner or the wrong technique. It’s a recognised clinical phenomenon, known as secondary non-response, and it’s more common than most people realise.

The clinical picture

Botox Type A vs Type B: What’s the Difference?

Botulinum Toxin Type A (BTX-A) is the most widely used anti-wrinkle treatment, and the one most people mean when they say ‘Botox’. With repeated treatment over months or years, a small proportion of patients develop reduced response to BTX-A — the effect becomes shorter, weaker, or stops appearing altogether, sometimes linked to the body building neutralising antibodies against it. Botulinum Toxin Type B (BTX-B) is a different serotype of the same toxin family, used in clinical practice as an alternative for patients in this situation. Clinical studies have shown BTX-B to be an effective and safe option for patients who no longer respond well to BTX-A, provided the dose is carefully individualised to the patient. Whether BTX-B — or an adjusted BTX-A protocol — is the right path for you depends on a proper clinical assessment, which is exactly what a consultation at Sol Clinic provides.

Our approach

Excellence in Medical Wellness & Regenerative Care

At Sol Clinic, every treatment plan begins with a comprehensive clinical assessment — not a standard protocol. Our multidisciplinary team, combining aesthetic, dermatological and regenerative medicine expertise, reviews your treatment history and current concerns before recommending a course of action tailored specifically to you. Because when it comes to treatment resistance, one size never fits all — dosing and formulation need to be individualised to get the best outcome.

Reception at Sol Clinic London, Harley Street Medical District

Founder

Led by Sol Reyes

Located in the heart of London’s Harley Street Medical District, Sol Reyes is an advanced aesthetics specialist with 18 years of international experience, known for precision-led, natural results. With training spanning Brazil, the United States and the United Kingdom, and four years of medical studies, Sol brings a clinical, detail-driven approach focused on safety, anatomy and long-term outcomes.

About Sol Clinic

What to expect

Your Private Consultation

Your history, reviewed

We discuss your treatment timeline, previous products used, and how your results have changed.

A proper clinical assessment

Sol evaluates your muscle response and rules out other causes for reduced results.

A tailored recommendation

You leave with a clear plan, including any alternative approaches suited to your case — explained fully, with no obligation.

Patient voices

4.9 on Google — Patient Testimonials

“I've seen several practitioners, but there's no one like Sol. I've been having my anti-wrinkle treatments and lip filler with her for four years. Excellent!”

Dayane R.Verified Google review

“I've been having treatments at Sol Clinic since 2020, and I only have praise for my experiences. The team is so attentive, professional and knowledgeable.”

M. de OliveiraVerified Google review

Results